Ndn - necdin, MAGE family member

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; gamma-tubulin binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nervous system development; neurotrophin TRK receptor signaling pathway; and regulation of transcription, DNA-templated. Located in cytoplasm. Human ortholog(s) of this gene implicated in Prader-Willi syndrome. Orthologous to human NDN (necdin, MAGE family member). [provided by Alliance of Genome Resources, Apr 2022]