Plekhf1 - pleckstrin homology and FYVE domain containing 1

Predicted to enable phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in endosome organization; positive regulation of autophagy; and protein localization to plasma membrane. Predicted to act upstream of or within positive regulation of intrinsic apoptotic signaling pathway. Predicted to be located in lysosome. Predicted to colocalize with endosome. Orthologous to human PLEKHF1 (pleckstrin homology and FYVE domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]