Pdcd6 - programmed cell death 6

Predicted to enable several functions, including metal ion binding activity; protein homodimerization activity; and ubiquitin ligase-substrate adaptor activity. Predicted to be involved in several processes, including mesenchymal cell differentiation; negative regulation of signal transduction; and positive regulation of cellular protein metabolic process. Predicted to act upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process and apoptotic process. Predicted to be located in several cellular components, including cytosol; endoplasmic reticulum exit site; and nucleoplasm. Predicted to be part of COPII vesicle coat and Cul3-RING ubiquitin ligase complex. Orthologous to human PDCD6 (programmed cell death 6). [provided by Alliance of Genome Resources, Apr 2022]