Mtss2 - MTSS I-BAR domain containing 2

Predicted to enable several functions, including GTPase activator activity; actin monomer binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including activation of GTPase activity; cell projection assembly; and cellular response to platelet-derived growth factor stimulus. Predicted to act upstream of or within lamellipodium organization. Predicted to be located in cortical actin cytoskeleton; lamellipodium; and ruffle membrane. Predicted to be active in actin cytoskeleton. Predicted to be intrinsic component of the cytoplasmic side of the plasma membrane. Orthologous to human MTSS2 (MTSS I-BAR domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]