Dtna - dystrobrevin, alpha

Enables PDZ domain binding activity and phosphatase binding activity. Predicted to be involved in synaptic signaling. Located in axon; cytoplasm; and sarcolemma. Is extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in cardiomyopathy and left ventricular noncompaction. Orthologous to human DTNA (dystrobrevin alpha). [provided by Alliance of Genome Resources, Apr 2022]