Piezo2 - piezo-type mechanosensitive ion channel component 2

Predicted to enable mechanosensitive cation channel activity. Predicted to be involved in cellular response to mechanical stimulus; detection of mechanical stimulus involved in sensory perception; and regulation of membrane potential. Predicted to act upstream of or within cation transport. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2). [provided by Alliance of Genome Resources, Apr 2022]