Afg3l2 - AFG3 like matrix AAA peptidase subunit 2

Predicted to enable metalloendopeptidase activity. Predicted to be involved in several processes, including calcium import into the mitochondrion; mitochondrial calcium ion homeostasis; and proteolysis. Predicted to act upstream of or within several processes, including mitochondrion organization; nervous system development; and righting reflex. Located in mitochondrion. Human ortholog(s) of this gene implicated in optic atrophy 12; spastic ataxia; spastic ataxia 5; and spinocerebellar ataxia type 28. Orthologous to human AFG3L2 (AFG3 like matrix AAA peptidase subunit 2). [provided by Alliance of Genome Resources, Apr 2022]