Spire1 - spire-type actin nucleation factor 1

Predicted to enable actin binding activity. Predicted to be involved in several processes, including cytoskeleton organization; cytoskeleton-dependent cytokinesis; and positive regulation of mitochondrial fission. Predicted to act upstream of or within behavioral fear response and dendritic spine development. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be integral component of mitochondrial outer membrane. Predicted to be active in cell cortex and cytoplasmic vesicle membrane. Predicted to colocalize with cleavage furrow. Orthologous to human SPIRE1 (spire type actin nucleation factor 1). [provided by Alliance of Genome Resources, Apr 2022]