Predicted to enable GTPase binding activity and isoleucine-tRNA ligase activity. Predicted to be involved in isoleucyl-tRNA aminoacylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Orthologous to human IARS1 (isoleucyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]