Dapk1 - death associated protein kinase 1

Predicted to enable several functions, including ATP binding activity; calmodulin binding activity; and syntaxin-1 binding activity. Predicted to be involved in several processes, including defense response to tumor cell; regulation of apoptotic process; and regulation of cellular protein metabolic process. Predicted to act upstream of or within extrinsic apoptotic signaling pathway via death domain receptors and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Predicted to be located in actin cytoskeleton and plasma membrane. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in urinary bladder cancer. Orthologous to human DAPK1 (death associated protein kinase 1). [provided by Alliance of Genome Resources, Apr 2022]