Lats2 - large tumor suppressor kinase 2

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including G1/S transition of mitotic cell cycle; hippo signaling; and negative regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to act upstream of or within several processes, including inner cell mass cell differentiation; keratinocyte differentiation; and negative regulation of canonical Wnt signaling pathway. Predicted to be located in centriolar satellite and cytosol. Predicted to be active in nucleus and spindle pole. Orthologous to human LATS2 (large tumor suppressor kinase 2). [provided by Alliance of Genome Resources, Apr 2022]