Depdc5 - DEP domain containing 5, GATOR1 subcomplex subunit

Predicted to contribute to GTPase activator activity. Predicted to be involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and regulation of autophagy. Predicted to be located in cytosol; lysosome; and perinuclear region of cytoplasm. Predicted to be part of GATOR1 complex. Predicted to be active in lysosomal membrane. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit). [provided by Alliance of Genome Resources, Apr 2022]