Tlr6 - toll-like receptor 6

Enables lipopeptide binding activity. Involved in several processes, including microglial cell activation; nitric oxide metabolic process; and response to bacterial lipoprotein. Predicted to be located in Golgi apparatus and membrane raft. Predicted to be part of Toll-like receptor 2-Toll-like receptor 6 protein complex. Predicted to be integral component of plasma membrane. Used to study bacterial pneumonia. Biomarker of perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in aspergillosis; asthma; infective endocarditis; rhinitis; and tuberculosis. Orthologous to human TLR6 (toll like receptor 6). [provided by Alliance of Genome Resources, Apr 2022]