Apbb2 - amyloid beta precursor protein binding family B member 2

Predicted to enable amyloid-beta binding activity. Predicted to be involved in several processes, including maintenance of lens transparency; negative regulation of cell cycle phase transition; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within extracellular matrix organization; generation of neurons; and regulation of apoptotic process. Predicted to be located in Golgi apparatus; early endosome; and endoplasmic reticulum. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease and cognitive disorder. Orthologous to human APBB2 (amyloid beta precursor protein binding family B member 2). [provided by Alliance of Genome Resources, Apr 2022]