Wdfy3 - WD repeat and FYVE domain containing 3

Predicted to enable 1-phosphatidylinositol binding activity and beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity. Predicted to be involved in aggrephagy. Predicted to be located in several cellular components, including autophagosome; inclusion body; and nucleus. Predicted to be extrinsic component of autophagosome membrane. Predicted to be part of Atg12-Atg5-Atg16 complex. Human ortholog(s) of this gene implicated in primary autosomal dominant microcephaly 18. Orthologous to human WDFY3 (WD repeat and FYVE domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]