Kdm2b - lysine demethylase 2B

Predicted to enable several functions, including histone H3-methyl-lysine-36 demethylase activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including brain development; cellular protein modification process; and embryonic morphogenesis. Predicted to act upstream of or within several processes, including histone H3-K36 demethylation; negative regulation of transcription by RNA polymerase II; and positive regulation of stem cell population maintenance. Predicted to be located in nucleus. Predicted to be part of PcG protein complex. Orthologous to human KDM2B (lysine demethylase 2B). [provided by Alliance of Genome Resources, Apr 2022]