Predicted to enable rRNA (uridine-2'-O-)-methyltransferase activity. Predicted to be involved in RNA methylation. Predicted to be located in nucleolus. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome. Orthologous to human MRM2 (mitochondrial rRNA methyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]