Rnf6 - ring finger protein 6

Predicted to enable DNA binding activity; androgen receptor binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including protein polyubiquitination; regulation of androgen receptor signaling pathway; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within negative regulation of axon extension. Predicted to be located in PML body; axon; and nuclear membrane. Predicted to be active in cytoplasm and nucleoplasm. Human ortholog(s) of this gene implicated in esophageal cancer and squamous cell carcinoma. Orthologous to human RNF6 (ring finger protein 6). [provided by Alliance of Genome Resources, Apr 2022]