Nrip1 - nuclear receptor interacting protein 1

Enables estrogen receptor binding activity. Predicted to be involved in several processes, including cellular response to estradiol stimulus; circadian regulation of gene expression; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in chromatin; cytosol; and nuclear lumen. Predicted to be part of histone deacetylase complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in CAKUT and osteoporosis. Orthologous to human NRIP1 (nuclear receptor interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]