Ikzf3 - IKAROS family zinc finger 3

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; histone deacetylase binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II; regulation of B cell activation; and regulation of apoptotic process. Predicted to act upstream of or within response to bacterium. Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human IKZF3 (IKAROS family zinc finger 3). [provided by Alliance of Genome Resources, Apr 2022]