Sgca - sarcoglycan, alpha

Predicted to enable calcium ion binding activity. Involved in response to denervation involved in regulation of muscle adaptation and skeletal muscle tissue regeneration. Predicted to be located in cell-cell junction; membrane raft; and sarcolemma. Predicted to be part of sarcoglycan complex. Biomarker of muscular atrophy. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2D and muscular dystrophy. Orthologous to human SGCA (sarcoglycan alpha). [provided by Alliance of Genome Resources, Apr 2022]