Wdr81 - WD repeat domain 81

Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and phosphatidylinositol 3-kinase regulator activity. Predicted to be involved in several processes, including aggrephagy; early endosome to late endosome transport; and protein stabilization. Predicted to be located in bounding membrane of organelle; cytosol; and mitochondrion. Predicted to be extrinsic component of endosome membrane. Human ortholog(s) of this gene implicated in cerebellar ataxia, mental retardation and dysequlibrium syndrome and hydrocephalus. Orthologous to human WDR81 (WD repeat domain 81). [provided by Alliance of Genome Resources, Apr 2022]