Chd3 - chromodomain helicase DNA binding protein 3

Predicted to enable ATP-dependent chromatin remodeler activity; double-stranded DNA helicase activity; and transcription cis-regulatory region binding activity. Predicted to be involved in chromatin remodeling; microtubule cytoskeleton organization; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin assembly or disassembly. Predicted to be located in centriolar satellite; cytoplasm; and nuclear lumen. Predicted to be part of NuRD complex. Biomarker of pancreatic carcinoma. Orthologous to human CHD3 (chromodomain helicase DNA binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]