Wnt3a - Wnt family member 3A

Predicted to enable several functions, including co-receptor binding activity; signaling receptor binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including canonical Wnt signaling pathway involved in heart development; nervous system development; and positive regulation of macromolecule metabolic process. Predicted to act upstream of or within several processes, including animal organ development; chordate embryonic development; and positive regulation of macromolecule metabolic process. Predicted to be located in cell surface. Predicted to be part of Wnt-Frizzled-LRP5/6 complex. Predicted to be active in extracellular space and glutamatergic synapse. Biomarker of hypothyroidism. Orthologous to human WNT3A (Wnt family member 3A). [provided by Alliance of Genome Resources, Apr 2022]