Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in histone acetylation. Predicted to act upstream of or within SMAD protein signal transduction; generation of neurons; and protein ubiquitination. Predicted to be located in nucleoplasm. Predicted to be part of histone acetyltransferase complex. Orthologous to human JADE2 (jade family PHD finger 2). [provided by Alliance of Genome Resources, Apr 2022]