Sh3pxd2b - SH3 and PX domains 2B

Predicted to enable SH2 domain binding activity; phosphatidylinositol phosphate binding activity; and superoxide-generating NADPH oxidase activator activity. Predicted to be involved in several processes, including animal organ development; osteoblast fate commitment; and podosome assembly. Predicted to be located in podosome. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Frank-Ter Haar syndrome. Orthologous to human SH3PXD2B (SH3 and PX domains 2B). [provided by Alliance of Genome Resources, Apr 2022]