Col4a4 - collagen type IV alpha 4 chain

Predicted to be an extracellular matrix structural constituent. Predicted to be involved in glomerular basement membrane development. Predicted to be located in membrane. Predicted to be part of collagen type IV trimer. Predicted to be active in basement membrane and extracellular space. Human ortholog(s) of this gene implicated in autosomal recessive Alport syndrome; benign familial hematuria; and end stage renal disease. Orthologous to human COL4A4 (collagen type IV alpha 4 chain). [provided by Alliance of Genome Resources, Apr 2022]