Cul3 - cullin 3

Predicted to enable several functions, including Notch binding activity; POZ domain binding activity; and cyclin binding activity. Predicted to be involved in several processes, including COPII vesicle coating; positive regulation of cell cycle process; and protein ubiquitination. Predicted to act upstream of or within several processes, including anaphase-promoting complex-dependent catabolic process; embryonic morphogenesis; and fibroblast apoptotic process. Predicted to be located in several cellular components, including Golgi apparatus; microtubule cytoskeleton; and sperm flagellum. Predicted to be part of Cul3-RING ubiquitin ligase complex. Human ortholog(s) of this gene implicated in pseudohypoaldosteronism. Orthologous to human CUL3 (cullin 3). [provided by Alliance of Genome Resources, Apr 2022]