Ndufs1 - NADH:ubiquinone oxidoreductase core subunit S1

Predicted to enable 4 iron, 4 sulfur cluster binding activity and electron transfer activity. Predicted to contribute to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in several processes, including mitochondrial electron transport, NADH to ubiquinone; mitochondrion organization; and regulation of mitochondrial membrane potential. Predicted to be located in mitochondrial inner membrane and mitochondrial intermembrane space. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in inherited metabolic disorder; mitochondrial complex I deficiency; and nuclear type mitochondrial complex I deficiency 5. Orthologous to human NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1). [provided by Alliance of Genome Resources, Apr 2022]