Sumo1 - small ubiquitin-like modifier 1

Predicted to enable enzyme binding activity; potassium channel regulator activity; and protein tag. Predicted to be involved in several processes, including negative regulation of protein import into nucleus; protein stabilization; and regulation of ion transmembrane transporter activity. Predicted to act upstream of or within PML body organization; protein localization to nuclear pore; and regulation of transcription, DNA-templated. Located in several cellular components, including XY body; dendrite; and fibrillar center. Colocalizes with PML body and heterochromatin. Human ortholog(s) of this gene implicated in orofacial cleft 10. Orthologous to human SUMO1 (small ubiquitin like modifier 1). [provided by Alliance of Genome Resources, Apr 2022]