Ercc5 - ERCC excision repair 5, endonuclease

Predicted to enable several functions, including DNA binding activity; RNA polymerase II complex binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including DNA repair; negative regulation of apoptotic process; and response to UV-C. Predicted to act upstream of or within UV protection; determination of adult lifespan; and nucleotide-excision repair. Predicted to be part of nucleotide-excision repair complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in cerebrooculofacioskeletal syndrome 3; melanoma; and xeroderma pigmentosum group G. Orthologous to human ERCC5 (ERCC excision repair 5, endonuclease). [provided by Alliance of Genome Resources, Apr 2022]