Il18r1 - interleukin 18 receptor 1

Predicted to enable interleukin-18 binding activity and interleukin-18 receptor activity. Predicted to be involved in several processes, including interleukin-18-mediated signaling pathway; negative regulation of cold-induced thermogenesis; and positive regulation of cytokine production. Predicted to act upstream of or within T-helper 1 cell differentiation; natural killer cell activation; and positive regulation of NIK/NF-kappaB signaling. Predicted to be part of interleukin-18 receptor complex. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL18R1 (interleukin 18 receptor 1). [provided by Alliance of Genome Resources, Apr 2022]