Trem1 - triggering receptor expressed on myeloid cells 1

Predicted to enable scaffold protein binding activity. Involved in several processes, including cellular response to lipid; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of macrophage chemotaxis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Used to study several diseases, including acute pancreatitis; bacterial sepsis; mesenteric vascular occlusion; middle cerebral artery infarction; and pleural empyema. Biomarker of congestive heart failure; mental depression; periodontitis; and rheumatoid arthritis. Human ortholog(s) of this gene implicated in bacterial sepsis and malaria. Orthologous to human TREM1 (triggering receptor expressed on myeloid cells 1). [provided by Alliance of Genome Resources, Apr 2022]