Predicted to enable WW domain binding activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to be located in nuclear envelope. Predicted to be active in endoplasmic reticulum. Orthologous to human SHISA5 (shisa family member 5). [provided by Alliance of Genome Resources, Apr 2022]