Uba7 - ubiquitin-like modifier activating enzyme 7

Predicted to enable ISG15 activating enzyme activity and ubiquitin-protein transferase activity. Predicted to be involved in ISG15-protein conjugation and cellular response to DNA damage stimulus. Predicted to act upstream of or within modification-dependent protein catabolic process. Predicted to be active in cytoplasm and nucleus. Orthologous to human UBA7 (ubiquitin like modifier activating enzyme 7). [provided by Alliance of Genome Resources, Apr 2022]