Parp3 - poly (ADP-ribose) polymerase family, member 3

Predicted to enable NAD DNA ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity; and protein ADP-ribosylase activity. Predicted to be involved in DNA metabolic process; protein ADP-ribosylation; and regulation of DNA metabolic process. Predicted to act upstream of or within several processes, including positive regulation of DNA ligation; protein localization to site of double-strand break; and regulation of mitotic spindle organization. Predicted to be located in intercellular bridge and nuclear body. Predicted to be active in nucleolus and site of double-strand break. Orthologous to human PARP3 (poly(ADP-ribose) polymerase family member 3). [provided by Alliance of Genome Resources, Apr 2022]