Hexa - hexosaminidase subunit alpha

Predicted to enable acetylglucosaminyltransferase activity; beta-N-acetylhexosaminidase activity; and protein heterodimerization activity. Predicted to be involved in ganglioside catabolic process and glycosaminoglycan biosynthetic process. Predicted to act upstream of or within several processes, including SMAD protein signal transduction; adult walking behavior; and nervous system development. Predicted to be located in azurophil granule and cytosol. Predicted to be active in lysosome and membrane. Human ortholog(s) of this gene implicated in Tay-Sachs disease. Orthologous to human HEXA (hexosaminidase subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]