Esam - endothelial cell adhesion molecule

Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in bicellular tight junction assembly; cellular protein localization; and regulation of actin cytoskeleton organization. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in adherens junction; bicellular tight junction; and plasma membrane. Predicted to be part of protein-containing complex. Orthologous to human ESAM (endothelial cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]