Npsr1 - neuropeptide S receptor 1

Predicted to enable neuropeptide receptor activity. Involved in several processes, including negative regulation of defecation; positive regulation of ERK1 and ERK2 cascade; and righting reflex. Predicted to be active in cytoplasm. Predicted to be integral component of plasma membrane. Biomarker of morphine dependence. Human ortholog(s) of this gene implicated in asthma; inflammatory bowel disease; newborn respiratory distress syndrome; and rheumatoid arthritis. Orthologous to human NPSR1 (neuropeptide S receptor 1). [provided by Alliance of Genome Resources, Apr 2022]