Amot - angiomotin

Predicted to enable angiostatin binding activity and signaling receptor activity. Predicted to be involved in several processes, including establishment of cell polarity involved in ameboidal cell migration; hippo signaling; and positive regulation of blood vessel endothelial cell migration. Predicted to act upstream of or within several processes, including gastrulation; negative regulation of GTPase activity; and vasculogenesis. Predicted to be located in several cellular components, including actin cytoskeleton; external side of plasma membrane; and ruffle. Predicted to be integral component of membrane. Predicted to be part of COP9 signalosome. Predicted to be active in several cellular components, including bicellular tight junction; cytoplasmic vesicle; and lamellipodium. Orthologous to human AMOT (angiomotin). [provided by Alliance of Genome Resources, Apr 2022]