Senp1 - SUMO specific peptidase 1

Predicted to enable SUMO-specific endopeptidase activity and SUMO-specific isopeptidase activity. Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic signaling pathway; and protein desumoylation. Predicted to act upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transcription by RNA polymerase II; and regulation of definitive erythrocyte differentiation. Predicted to be located in focal adhesion; nuclear membrane; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human SENP1 (SUMO specific peptidase 1). [provided by Alliance of Genome Resources, Apr 2022]