Lgr5 - leucine rich repeat containing G protein coupled receptor 5

Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in several processes, including activation of adenylate cyclase activity; adenylate cyclase-activating G protein-coupled receptor signaling pathway; and positive regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within several processes, including epithelial cell proliferation involved in renal tubule morphogenesis; hair follicle development; and oocyte differentiation. Predicted to be located in nucleoplasm and trans-Golgi network membrane. Predicted to be integral component of plasma membrane. Orthologous to human LGR5 (leucine rich repeat containing G protein-coupled receptor 5). [provided by Alliance of Genome Resources, Apr 2022]