Casp14 - caspase 14

Predicted to enable cysteine-type endopeptidase activity involved in execution phase of apoptosis. Predicted to be involved in cornification; execution phase of apoptosis; and proteolysis. Located in keratin filament and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis. Orthologous to human CASP14 (caspase 14). [provided by Alliance of Genome Resources, Apr 2022]