Nin - ninein

Predicted to enable microtubule minus-end binding activity. Predicted to be involved in centrosome localization; microtubule cytoskeleton organization; and protein localization. Predicted to act upstream of or within several processes, including generation of neurons; negative regulation of protein localization to centrosome; and positive regulation of microtubule polymerization. Predicted to be located in several cellular components, including axonal growth cone; microtubule cytoskeleton; and nuclear lumen. Predicted to be part of centriolar subdistal appendage and ciliary transition fiber. Predicted to be active in centriole; mitotic spindle pole; and pericentriolar material. Human ortholog(s) of this gene implicated in Seckel syndrome 7. Orthologous to human NIN (ninein). [provided by Alliance of Genome Resources, Apr 2022]