Mycn - MYCN proto-oncogene, bHLH transcription factor

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and kinase binding activity. Predicted to be involved in negative regulation of reactive oxygen species metabolic process and regulation of gene expression. Predicted to act upstream of or within several processes, including embryonic digit morphogenesis; negative regulation of astrocyte differentiation; and skeletal system morphogenesis. Predicted to be located in nucleolus and nucleoplasm. Human ortholog(s) of this gene implicated in Feingold syndrome. Orthologous to human MYCN (MYCN proto-oncogene, bHLH transcription factor). [provided by Alliance of Genome Resources, Apr 2022]