Nlrc4 - NLR family, CARD domain containing 4

Predicted to enable several functions, including ATP binding activity; caspase binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including positive regulation of proteolysis; regulation of gene expression; and response to bacterium. Predicted to act upstream of or within regulation of apoptotic process and regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be located in cytosol. Predicted to be part of IPAF inflammasome complex. Human ortholog(s) of this gene implicated in familial cold autoinflammatory syndrome 4. Orthologous to human NLRC4 (NLR family CARD domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]