Isg15 - ISG15 ubiquitin-like modifier

Predicted to enable integrin binding activity; protein tag; and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in several processes, including cellular protein metabolic process; defense response to other organism; and positive regulation of cytokine production. Predicted to act upstream of or within response to bacterium. Predicted to be located in extracellular region. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 38. Orthologous to human ISG15 (ISG15 ubiquitin like modifier). [provided by Alliance of Genome Resources, Apr 2022]