Tardbp - TAR DNA binding protein

Enables RNA binding activity. Involved in positive regulation of insulin secretion and response to endoplasmic reticulum stress. Located in cytoplasm and nuclear lumen. Human ortholog(s) of this gene implicated in Parkinson's disease; amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 10; and motor neuron disease. Orthologous to human TARDBP (TAR DNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]