Pink1 - PTEN induced kinase 1

Enables protein serine/threonine kinase activity and ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to hydrogen sulfide; negative regulation of cell death; and positive regulation of NMDA glutamate receptor activity. Located in endoplasmic reticulum; growth cone; and mitochondrial envelope. Used to study Parkinson's disease and Parkinsonism. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Orthologous to human PINK1 (PTEN induced kinase 1). [provided by Alliance of Genome Resources, Apr 2022]