Cldn19 - claudin 19

Predicted to enable structural molecule activity. Predicted to be involved in several processes, including bicellular tight junction assembly; positive regulation of macromolecule metabolic process; and regulation of transepithelial transport. Predicted to act upstream of or within apical junction assembly; neuronal action potential propagation; and tight junction organization. Predicted to be located in several cellular components, including apical junction complex; basolateral plasma membrane; and perinuclear region of cytoplasm. Predicted to be active in bicellular tight junction and plasma membrane. Human ortholog(s) of this gene implicated in renal hypomagnesemia 5 with ocular involvement. Orthologous to human CLDN19 (claudin 19). [provided by Alliance of Genome Resources, Apr 2022]